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Welcome to the Crowne Plaza Houston Hotel near Reliant Park / Medical Center. Our recently renovated, full-service hotel is located in Houston’s Inner Loop and less than 10 miles south of downtown Houston, convenient to US-59 and I-610. The hotel is located directly across from and within walking distance to Reliant Park’s Stadium, The Astrodome, Reliant Center and Reliant Arena. The Crowne Plaza Houston Medical Center Hotel is minutes from the best health care at the world-renowned Texas Medical Center.